Molecular Medicine Select
نویسنده
چکیده
From Alzheimer’s disease and the obesity epidemic to the chronic health effects of certain viral infections, scientists in academia and big pharma are seeking new therapeutic targets and strategies to tackle these diseases. However, as discussed in this Molecular Medicine Select, designing more effective drugs with fewer side effects that fight the disease itself and not just the symptoms requires a thorough understanding of the underlying mechanisms of disease pathogenesis.
منابع مشابه
Molecular Medicine Select
The recent generation of induced pluripotent stem (iPS) cells from adult human somatic cells has intensified interest in cellular therapies for treating human disease. This issue’s Molecular Medicine Select highlights progress in overcoming barriers to the use of transplanted cells. These achievements include the treatment of sickle cell anemia in mice using genetically repaired iPS cells, the ...
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Various formulations of selenium and vitamin E, both essential human dietary components, have been shown to possess a therapeutic and preventive effect against prostate cancer. Fortuitous results of clinical trials also implied a risk-reduction effect of selenium and vitamin E supplements. The Selenium and Vitamin E Cancer Prevention Trial (SELECT), using oral selenium and vitamin E supplementa...
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Objective(s): Tuberculosis (TB) is still one of the problematic infectious diseases in developing countries, especially in Iran. In the present study, we applied ribosome display technique to select single chain variable fragments (scFvs) specific for the 6-kDa early secretory antigenic target (ESAT-6) antigen of Mycobacterium tuberculosis from a mouse scFv library. Materials and Methods: The g...
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Acquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus (HIV), has become, because of the rapid spread of the disease, a serious global problem and cannot be treated. Recent studies indicate that VIF is a protein of HIV to prevent all of human immunity to attack HIV. Molecular compounds of traditional Chinese medicine (TCM) database filtered through molecular docking a...
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ورودعنوان ژورنال:
- Cell
دوره 140 شماره
صفحات -
تاریخ انتشار 2010